Pioneering Gamma Stimulation Therapy

This groundbreaking science may hold the key to solving multiple brain disorders. Cognito Therapeutics is a clinical stage company developing device-based therapies and services to pioneer this approach. Gamma stimulation is a non-invasive brain stimulation technique that could provide dramatic benefits in Alzheimer’s Disease.

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Our Approach

Empathy-driven design, with people at the center

We recognize the complexities of day-to-day life with Alzheimer’s Disease. Our aim is to develop a treatment that recognizes these realities and supports individuals and caregivers throughout the care journey. To make this mission a reality, we work closely with the individuals we are designing for to root ourselves in their evolving needs and challenges.

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1 in 9

Adults over the age of 65 in the U.S. alone are living with Alzheimer's Disease.

The Science

Groundbreaking science is our core

Cognito founders Li-Huei Tsai, PhD, and Ed Boyden, PhD, pioneers in brain research, published a landmark study showing dramatic benefit in treating Alzheimer’s using a non-invasive brain stimulation technique. These compelling results are the foundation of the clinical trials we are conducting today.

Knowing that in Alzheimer’s Disease there is a deficiency in gamma brainwave frequencies, our founders discovered that stimulating the brain at 40Hz had the effect of reactivating the immune system in the brain. This effect correlated with a reduction in amyloid plaques and tau tangles, typical hallmarks of the disease.

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In the Press

About Us


We are a team of inspired and inquisitive scientists, engineers, and designers. Our founders are scientific leaders in the fields of memory, learning, and neuroscience.

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Le-Huei Tsai

Li-Huei Tsai, PhD


Dr. Tsai is a founder of Cognito Therapeutics and the Picower Professor of Neuroscience and Director of The Picower Institute of Learning and Memory at MIT. Dr. Tsai's research has focused on elucidating pathogenic mechanisms underlying neurological disorders that affect learning and memory.

Ed Boyden

Ed Boyden, PhD


Dr. Boyden is a founder of Cognito Therapeutics and Y. Eva Tan Professor in Neurotechnology and Professor of Biological Engineering and Brain and Cognitive Sciences at the MIT Media Lab and MIT McGovern Institute. Dr. Boyden’s research focuses on developing tools for analyzing and repairing complex biological systems and using these tools to elucidate fundamental principles about the biological function of these systems.


Join the Team

We are a team of inspired and inquisitive scientists, engineers, and designers. We have a passion for helping others and are clever problem-solvers who value interdisciplinary collaboration and diverse perspectives. We are looking for exceptional individuals who share the ideals of our growing team and our passion for developing life-changing therapies. Cognito has locations in Boston and the San Francisco Bay Area.

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